Medical Uses Of Cannabinoids:
Drugs containing cannabinoids could also be helpful in treating certain rare sorts of epilepsy, nausea and vomiting related to cancer chemotherapy, and loss of appetite and weight loss related to HIV/AIDS. additionally , some evidence suggests modest benefits of cannabis or cannabinoids for chronic pain and MS symptoms. Cannabis isn’t helpful for glaucoma.
Potent cannabinoids receptors, endocannabinoids and therefore the enzymes liable for their biosynthesis and degradation constitute the endocannabinoid system. In recent decades, the endocannabinoid system has attracted considerable interest as a possible therapeutic target in numerous pathological conditions.
Its involvement in several physiological processes is documented , like in energy balance, appetite stimulation, vital sign , pain modulation, embryogenesis, nausea and vomiting control, memory, learning and immune reaction , among others, also as in pathological conditions where it exerts a protective role within the development of certain disorders.
As a result, it’s been reported that changes in endocannabinoid levels could also be associated with neurological diseases like paralysis agitans , Huntington’s chorea , Alzheimer’s disease and MS , also as anorexia and irritable bowel syndrome. Alterations within the endocannabinoid system have also been related to cancer, affecting the expansion , migration and invasion of some tumours.
Below are the some of the major diseases than can be cured with Cannabis or specifically with the chemical “Cannabinoid”.
Cannabis for Pain Management:
⦁ A 2018 review of 16 studies of cannabis-based medicines for neuropathic pain, most of which tested a cannabinoid preparation called nabiximols (brand name Sativex; a mouth spray containing both THC and CBD that’s approved in some countries but not within the United States), found low- to moderate-quality evidence that these medicines produced better pain relief than placebos did. However, the info couldn’t be considered reliable because the studies included small numbers of individuals and should are biased. People taking cannabis-based medicines were more likely than those taking placebos to drop out of studies due to side effects.
⦁ A 2015 review of 28 studies (2,454 participants) of cannabinoids during which chronic pain was assessed found the studies generally showed improvements in pain measures in people taking cannabinoids, but these didn’t reach statistical significance in most of the studies. However, the typical number of patients who reported a minimum of a 30 percent reduction in pain was greater with cannabinoids than with placebo.
Cannabis to cure Opioids:
A 2017 review checked out studies in people during which medical use of cannabinoids were administered along side opioids to treat pain. These studies were designed to work out whether cannabinoids could make it possible to regulate pain with smaller amounts of opioids. there have been 9 studies (750 total participants), of which 3 (642 participants) used a high-quality study design during which participants were randomly assigned to receive cannabinoids or a placebo. The results were inconsistent, and none of the high-quality studies indicated that cannabinoids could lead on to decreased opioid use.
⦁ Researchers have checked out statistical data on groups of individuals to ascertain whether access to cannabis (for example, through “medical marijuana laws”—state laws that allow patients with certain medical conditions to urge access to cannabis)—is linked with changes in opioid use or with changes in harm related to opioids. The findings are inconsistent.
⦁ States with Medical use of cannabinoids laws were found to possess lower prescription rates both for opioids and for all drugs that cannabis could substitute for among people on Medicare. However, data from a national survey (not limited to people on Medicare) showed that users of medical marijuana were more likely than nonusers to report taking prescribed drugs
Cannabis for Cancer Treatment:
The bottom line is that immediately there isn’t enough reliable evidence to prove that any sort of cannabis can effectively treat cancer in patients. This includes hemp oil, cannabis oil or the active chemicals found within the cannabis plant (cannabinoids) – whether natural or man-made.
Many researchers worldwide are actively investigating Medical use of cannabinoids, and Cancer Research UK is supporting a number of this work. These studies use highly purified chemicals found within the cannabis plant, or lab-made versions of them, and there’s genuine interest in these as potential cancer treatments. But this is often very different to street-bought cannabis and hemp oil available online or on the main street , that there’s no evidence of any impact on cancer.